Comprehensive guide for NEET preparation, covering all key concepts, reactions, and tests. Click a chapter to view its notes.
Saturated hydrocarbons with single C-C bonds. General formula: CₙH₂ₙ₊₂. Non-polar, insoluble in water, boiling points increase with molecular weight (e.g., CH₄: -161°C, C₄H₁₀: -0.5°C). Density < 1 g/cm³.
NEET Tip: Questions often focus on trends in physical properties or halogenation products.
Free radical mechanism for halogenation: Initiation (X₂ → 2X•), Propagation (R-H + X• → R• + HX; R• + X₂ → R-X + X•), Termination (R• + X• → R-X). NEET Note: Chlorination is non-selective, forming multiple products.
No specific functional group test; identified by inert nature and combustion products (CO₂, H₂O). NEET MCQ Trap: Distinguish alkanes from alkenes using bromine test.
Unsaturated hydrocarbons with one C=C bond. General formula: CₙH₂ₙ. Non-polar, insoluble in water, boiling points slightly higher than alkanes (e.g., C₂H₄: -103°C). Cis-trans isomerism possible.
NEET Tip: Questions on geometrical isomerism and Markovnikov’s rule are common.
Electrophilic addition: C=C π-bond breaks, electrophile (H⁺, X⁺) adds, forming carbocation or cyclic intermediate. NEET Note: Markovnikov’s rule governs addition; anti-Markovnikov in hydroboration.
Unsaturated hydrocarbons with one C≡C bond. General formula: CₙH₂ₙ₋₂. Slightly polar (terminal alkynes), boiling points higher than alkenes (e.g., C₂H₂: -84°C).
NEET Tip: Terminal alkynes’ acidity is frequently tested.
Electrophilic addition; terminal alkynes form acetylide ions (R-C≡C-H → R-C≡C⁻) due to acidity. NEET Note: Hydration follows Markovnikov’s rule.
Contain benzene ring or derivatives. Stable due to resonance. General formula: CₙHₙ (simple aromatics). High boiling points (e.g., C₆H₆: 80°C), insoluble in water.
NEET Tip: Resonance and electrophilic substitution are key concepts.
Electrophilic aromatic substitution: Electrophile replaces H⁺ via sigma complex (arenium ion). NEET Note: Ortho-para vs. meta-directing groups are crucial.
No specific test; identified by stability and substitution products. NEET MCQ Trap: Distinguish from alkenes (no Baeyer’s test).
Contain C-X bond (X = F, Cl, Br, I). Polar, higher boiling points than hydrocarbons (e.g., CH₃Cl: -24°C). Haloarenes are less reactive due to resonance.
NEET Tip: Questions often test Sₙ1 vs. Sₙ2 mechanisms.
Sₙ1 (carbocation, tertiary halides), Sₙ2 (concerted, primary halides), E1/E2 similar. Haloarenes undergo nucleophilic aromatic substitution. NEET Note: Sₙ2 favors polar aprotic solvents.
Contain -OH group. Polar, H-bonding, high boiling points (e.g., CH₃OH: 64.7°C). Solubility decreases with chain length.
NEET Tip: Questions on Lucas test and oxidation products are frequent.
Dehydration (E1 for 2°/3°, E2 for 1°), oxidation (loss of H₂), nucleophilic attack in esterification. NEET Note: Tertiary alcohols favor Sₙ1 with HX.
Contain -OH on benzene. Acidic (pKa ~10), soluble in water, high boiling point (C₆H₅OH: 182°C).
NEET Tip: Acidity and electrophilic substitution are key.
Electrophilic substitution (activated ring, ortho-para directing); Reimer-Tiemann involves dichlorocarbene. NEET Note: Phenol’s acidity is due to resonance-stabilized phenoxide ion.
Contain C-O-C linkage. Non-polar, low boiling points (e.g., CH₃OCH₃: -24°C), used as solvents.
NEET Tip: Williamson synthesis is a high-weightage topic.
Sₙ1/Sₙ2 cleavage; tertiary ethers favor Sₙ1. NEET Note: Aryl ethers resist cleavage due to resonance.
No specific test; identified by inertness and solubility. NEET MCQ Trap: Ethers vs. alcohols (no H-bonding in ethers).
Contain -CHO group. Polar, boiling points higher than hydrocarbons (e.g., CH₃CHO: 20°C). Soluble in water (H-bonding).
NEET Tip: Aldehyde tests (Tollens’, Fehling’s) are high-yield.
Nucleophilic addition to C=O; Cannizzaro involves hydride transfer; Aldol forms β-hydroxy aldehyde. NEET Note: Formaldehyde undergoes Cannizzaro, not Aldol.
Contain C=O group. Polar, boiling points higher than aldehydes (e.g., CH₃COCH₃: 56°C). Less reactive than aldehydes.
NEET Tip: Iodoform test and reduction reactions are key.
Nucleophilic addition to C=O, slower than aldehydes due to steric hindrance. NEET Note: Acetone gives iodoform test.
Contain -COOH group. Acidic (pKa ~4-5), high boiling points (e.g., CH₃COOH: 118°C), H-bonding, water-soluble.
NEET Tip: Acidity order and esterification are high-yield topics.
Nucleophilic acyl substitution in esterification; HVZ involves α-halogenation. NEET Note: Acidity order: Cl-CH₂COOH > CH₃COOH > C₆H₅COOH.
Contain -NH₂, -NHR, or -NR₂. Basic, H-bonding, boiling points lower than alcohols (e.g., CH₃NH₂: -6°C). Solubility: 1° > 2° > 3°.
NEET Tip: Basicity order and Hinsberg test are crucial.
Nucleophilic substitution in carbylamine; basicity due to lone pair donation. NEET Note: Basicity order: 2° > 1° > 3° (in aqueous solution).
Contain -C≡N group. Polar, high boiling points (e.g., CH₃CN: 82°C), toxic.
NEET Tip: Reduction and hydrolysis products are key.
Nucleophilic addition to C≡N bond. NEET Note: Partial hydrolysis gives amides.
No specific test; identified by hydrolysis to carboxylic acids. NEET MCQ Trap: Nitriles vs. isocyanides (hydrolysis products differ).
Contain -NC group. Foul smell, boiling points similar to nitriles (e.g., CH₃NC: 59°C).
NEET Tip: Carbylamine reaction is a must-know.
Nucleophilic addition to C=N bond. NEET Note: Isocyanides give N-methyl amines on hydrolysis.
Foul smell; confirmed by hydrolysis to N-methyl amines. NEET MCQ Trap: Isocyanides vs. nitriles (foul smell, different hydrolysis).
Contain -CONH₂ group. Polar, high boiling points (e.g., CH₃CONH₂: 221°C), H-bonding.
NEET Tip: Hoffmann bromamide is high-yield.
Nucleophilic acyl substitution; Hoffmann involves nitrene intermediate. NEET Note: Decreases carbon chain by one.
Contain -CO-O-CO- group. Reactive, high boiling points (e.g., (CH₃CO)₂O: 140°C).
NEET Tip: Reactions with nucleophiles are key.
Nucleophilic acyl substitution. NEET Note: More reactive than esters.
No specific test; identified by hydrolysis to acids. NEET MCQ Trap: Anhydrides vs. esters (faster hydrolysis).
Contain -COOR group. Pleasant smell, moderate boiling points (e.g., CH₃COOCH₃: 57°C).
NEET Tip: Esterification and hydrolysis are high-yield.
Nucleophilic acyl substitution; tetrahedral intermediate. NEET Note: Acidic vs. basic hydrolysis products differ.
Contain -NO₂ group. Polar, high boiling points (e.g., C₆H₅NO₂: 211°C), insoluble in water.
NEET Tip: Reduction products are key.
Electrophilic substitution for nitration; reduction via electron transfer. NEET Note: Nitro group is meta-directing.
Reduction to amines, followed by amine tests (e.g., diazotization). NEET MCQ Trap: Nitro vs. nitrites (different reduction products).
Contain -N₂⁺ group. Unstable, decompose above 5°C, used in synthesis.
NEET Tip: Coupling and Sandmeyer reactions are high-yield.
Nucleophilic attack in coupling; radical mechanism in Sandmeyer. NEET Note: Coupling occurs at para position of phenol.
Polyhydroxy aldehydes/ketones. General formula: Cₙ(H₂O)ₙ. Classified as monosaccharides (glucose, fructose), disaccharides (sucrose, maltose), polysaccharides (starch, cellulose). Functions: Energy source, structural (cellulose).
NEET Tip: Reducing vs. non-reducing sugars (sucrose is non-reducing).
Amino acids: Contain -NH₂ and -COOH (e.g., glycine, alanine). Proteins: Polypeptides of amino acids, form enzymes, structural components (keratin). Zwitterion structure at isoelectric point.
NEET Tip: Ninhydrin and Biuret tests are frequently tested.
Macromolecules from monomers. Types: Natural (cellulose, proteins), Synthetic (nylon, PVC). Addition (polythene) vs. condensation (nylon-6,6). Uses: Plastics (PVC: pipes), fibers (nylon: textiles), rubbers (neoprene: belts).
NEET Tip: Monomers and polymer types are high-yield.
Medicines: Analgesics (aspirin), antipyretics (paracetamol), antibiotics (penicillin). Daily life: Soaps (sodium stearate), detergents (sodium lauryl sulfate), antiseptics (Dettol: chloroxylenol), disinfectants (phenol).
NEET Tip: Distinguish antiseptics vs. disinfectants; drug structures are key.